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urea cycle

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
L-aspartate + L-citrulline + ATP <=> H+ + argininosuccinate + diphosphate + AMP 6.3.4.5 argininosuccinate synthase

L-ornithine + Carbamoyl_phosphate <=> H+ + L-citrulline + phosphate 2.1.3.3 ornithine carbamoyltransferase
2.1.3.6 putrescine carbamoyltransferase
3.5.3.12 agmatine deiminase



argininosuccinate <=> L-arginine + fumarate 4.3.2.1 argininosuccinate lyase
4.3.2.2 adenylosuccinate lyase


ATP + HCO3- + NH3 <=> ADP + phosphate + Carbamoyl_phosphate + H+ 6.3.4.16 carbamoyl-phosphate synthase (ammonia)
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)


H2O + L-arginine <=> Urea + L-ornithine 3.5.3.1 arginase
3.5.3.7 guanidinobutyrase


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